Huntington's disease
Title: Huntington's disease
Category: Recreation & Sports / Health Care | Words: 1117 | Pages: 4.8 (approximately 235 words/page)
Huntington's disease
Huntington's Background
Huntington's disease is inherited as an autosomal dominant disease that gives rise to
progressive, elective (localized) neural cell death associated with choreic movements
(uncontrollable movements of the arms, legs, and face) and dementia. It is one of the
more common inherited brain disorders. About 25,000 Americans have it and another
60,000 or so will carry the defective gene and will develop the disorder as they age.
Physical deterioration occurs over a period of 10 to 20 years,
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The Neurology articles explains how HD patients have much
higher deletion levels than agematched controls in the frontal and temporal lobes of the
cortex, whereas the article from Times Medical Writer focuses on a possible treatment
resulting from a finding of a second protein called HAP-1, that binds itself to the
huntingtin molecule only in the brain. Both conclude that HD is a mutation that causes
damage to brain cells further in a person's life.
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