Flowers for Algernon has several conflicts, which can be classified into 3 categories; protagonist versus nature, protagonist versus self, and protagonist versus society. Protagonist versus nature is Charlie trying to increase his natural IQ of 68 and suppress the effects which would occur naturally as seen in Algernon. The mental regression which could be seen in Algernon, on which the operation was performed earlier, is what Charlie is trying to battle by "[practising] very hard", though his …showed first 75 words of 378 total…

…showed last 75 words of 378 total…quest for true acceptance, however hard he tries, is always fruitless. Drs. Strauss and Nemur look down on him and treat him as an experiment; someone who does not deserve good treatment. The conflicts of this novel intertwine Charlie in ways that intertwines with the other conflictspreventing them from being resolved without the fall or humiliation of the other. Flowers for Algernon contains conflicts both internal and external that prevents a solution that benefits all.