Introduction Vitamin B12 deficiency is a systemic disease that often affects the nervous system, and one of the most prevalent manifestations is Sub-acute Combined Degeneration of the Spinal Cord (SACD), which is encountered regularly by neurologists. It primarily affects the posterior and lateral columns of the spinal cord white matter resulting in paraesthesia, ataxic gait and loss of vibration and proprioception sense (Metz, 1992). The details of which will be discussed later in the paper. SACD …showed first 75 words of 2001 total…

…showed last 75 words of 2001 total…New York. pp.523-524. Locatelli, ER, Laureno, R, Ballard, P and Mark, AS. (1999) MRI in Vitamin B12 Deficiency Myelopathy. 26(1); 60-63. Markle, HV. (1996) Cobalamin. Critical Review of Clinical Laboratory Science. 33(4); 247-256. Metz, J. (1992) Cobalamin Deficiency and the Pathogenesis of Nervous System Disease. Annual Review of Nutrition. 12; 59-79. Patten, J. (1996) Neurological Differential Diagnosis. Springer. New York. Pp.234-235. Walton, L. (1989) Essentials of Neurology. 6th edn. Churchill Livingstone. London.p.314. Yen, A. (2000) Department of Neurology. Baylor College of